Showing posts with label male factor. Show all posts
Showing posts with label male factor. Show all posts

Thursday, March 3, 2011

How we got to IVF & Current Status

Last year, after going through two miscarriages at about 8 weeks, I had a bazillion tests done to see what could be wrong. We found nothing. No uterine factors, no immunology issues, no clotting factors, no infection. The Wacky Wicketeer and I were both karyotyped after the first miscarriage, which showed that we, ourselves, had no major chromosome defect that might be contributing to the loss. My general practitioner did find that I had a severe vitamin D deficiency. However, my Reproductive Endocrinologists (REs) would not attribute my losses to this factor. (Despite the fact that there are recent studies coming out showing a possible relationship between uterine lining and vitamin D.) Go here for more information on causes of Recurrent Pregnancy Loss (RPL): http://www.asrm.org/uploadedFiles/ASRM_Content/Resources/Patient_Resources/Fact_Sheets_and_Info_Booklets/recurrent_preg_loss.pdf)

We were very disappointed in the attention and lack of customer service we were receiving at our first clinic. So, we went to a new one last fall.

Our new RE, Dr. "Analytical", diagnosed me with a mild form of Polycystic Ovarian Syndrome (PCOS). You can learn more about PCOS here: http://haveababy.com/infertility-education/causes-of-infertility/pcos.html. PCOS is a syndrome, thus it occurs on a spectrum. At my end of the spectrum, I still ovulate regularly, but my eggs are immature and/or poor quality.

Dr. Analytical has a theory that, between poor-quality eggs caused by PCOS, and abnormal sperm, as exemplified by the Wacky Wicketeer's abnormal sperm morphology, we end up with a non-viable embryo on the rare occasions that sperm actually fertilizes egg. This then results in a pregnancy loss.

Dr. Analytical has explained to us that our best chance at having a biological child is through In Vitro Fertilization (IVF) with Intra-cytoplasmic Sperm Injection (ICSI) and genetic screening. In this way, we are the most likely to become pregnant with a viable embryo.

So, here we are. We decided to do IVF with ICSI and genetic screening, and are now in the midst of treatment. It is a trying process, and we are attempting to approach it with grace, with respect for our marriage, and with love for the embryos conceived in the process. I'll explain more of the details in another post, but for now, know that we have five, maybe six, embryos in their first home at the clinic, each fighting to grow. Please send them, and us, your prayers, hope, love, luck, and well-wishes. Thanks in advance, and lots of babydust to those looking for it!

Thursday, September 23, 2010

Check it out: Info from "The Disappearing Male"

Most of you know that so far, our fertility diagnosis is one of male factor infertility. Specifically, the Wacky Wicketeer has abnormal sperm morphology, or too low a number of properly-shaped sperm, and sometimes borderline sperm motility. This male factor infertility issue is becoming more and more common, and for us, is likely one of the factors involved in our two pregnancy losses.

When the Wacky Wicketeer and I discovered our infertile status, it was estimated that one in ten couples of child-bearing age in the U.S. was infertile. That number has already gone up to one in eight. Moreover, reproductive and other problems in boys are on an alarming increase.

A little less than two years ago, and replayed earlier this year, CBC, a respected Canadian television network, did a documentary as part of its Doc Zone series, called "The Disappearing Male". Unfortunately, the website only allows those in Canada to view it online, here: http://www.cbc.ca/video/#/Shows/Doc_Zone/ID=1233750780

But even if you can't watch the video, you can find some of the alarming facts on their fact sheet on male infertility, such as: "The average sperm count of a North American college student today is less than half of what it was 50 years ago." They also include some great explanations as to just how and why this appears to be happening, in their document, "Backgrounder: Endocrine 101".

While the current state of information in this arena is fluctuating and largely theoretical, the statistics are staggering, and the anecdotes are heartbreaking. The Wacky Wicketeer and I have taken the approach that, if there is something we can do about it in our lives, then we might as well do it. Some examples of the steps we have taken include: Getting rid of all our kitchen plastics other than numbers 1, 2, 4 and 5; Not using any plastics in the microwave; Getting a new couch; Dusting and vaccuming more frequently; Decreasing products we use with phthalates and parabens, opting for goods that use other, known and recognizable ingredients.

I hope you'll take a minute to look at the CBC info, and consider what you can do to make a difference for the children and future children in your life.